Metal oxide nanoparticles – commonly used as food coloring and anti-caking agents in the commercial ingredients industry – may damage parts of the human intestine, according to new research by Cornell and Binghamton University scientists.
We found that specific nanoparticles – titanium dioxide and silicon dioxide – ordinarily used in food may negatively affect intestinal functionality. They have a negative effect on key digestive and absorptive proteins.Elad Tako, Associate Professor, Food Science , Cornell University
In their research, the group used human-relevant doses of titanium dioxide and silicon dioxide in the Tako laboratory’s in vivo system, which offers a health response similar to the human body’s.
The scientists injected the nanoparticles in chicken eggs. After the chickens hatched, the scientists detected changes in the functional, morphological and microbial biomarkers in the blood, the duodenum (upper intestine) and the cecum (a pouch connected to the intestine).
“We are consuming these nanoparticles on a daily basis,” said Tako. “We don’t really know how much we consume; we don’t really know the long-term effects of this consumption. Here, we were able to demonstrate some of these effects, which is a key to understanding gastrointestinal health and development.”
“Based on the information, we suggest simply being aware,” Tako said. “Science needs to conduct further investigations based on our findings. We are opening the door for discussion.” (MSM/Newswise)