A recent systematic review of observational studies evaluated the potential association between radiofrequency (RF) electromagnetic field exposure and the risk of developing tumors. Investigators examined cohort and case-control studies from 1994 to 2022, covering 119 exposure sources across 22 countries. The review focused on neoplasms in the central nervous system—such as brain tumors, acoustic neuromas, and meningiomas—and included salivary gland tumors and pediatric brain cancers. Despite growing public concerns about the impact of wireless technology, the findings suggest that RF exposure does not significantly increase cancer risk.

Types of Exposure and Tumor Types Investigated

The review analyzed three categories of RF exposure:

• Head-localized near-field exposure: Primarily from mobile or cordless phone use.

• Far-field environmental exposure: Linked to fixed-site transmitters like cell towers.

• Occupational exposure: Involving handheld transceivers or RF-emitting equipment in the workplace.

Tumors of interest included gliomas, meningiomas, pituitary tumors, acoustic neuromas, salivary gland tumors, and childhood brain tumors, along with leukemia.

Results: No Clear Evidence of Elevated Tumor Risk

The meta-analysis combined the results using random effects and mixed models to assess potential links between RF exposure and cancer risk. Key findings include:

Mobile phone use vs. non-use:

• Glioma (mRR: 1.01; 95% CI: 0.89–1.13)

• Meningioma (mRR: 0.92; 95% CI: 0.82–1.02)

• Acoustic neuroma (mRR: 1.03; 95% CI: 0.85–1.24)

• Pituitary tumors (mRR: 0.81; 95% CI: 0.61–1.06)

• Salivary gland tumors (mRR: 0.91; 95% CI: 0.78–1.06)

• Pediatric brain tumors (mRR: 1.06; 95% CI: 0.74–1.51)

There was no observable increase in risk for glioma, meningioma, or acoustic neuroma based on the duration of mobile phone use, cumulative call time, or the total number of calls.

Similarly, cordless phone use did not show a significant association with the development of glioma (mRR: 1.04; 95% CI: 0.74–1.46), meningioma (mRR: 0.91; 95% CI: 0.70–1.18), or acoustic neuroma (mRR: 1.16; 95% CI: 0.83–1.61).

Environmental and Occupational Exposure Findings

The review also investigated far-field exposure from fixed-site transmitters, such as cell towers, and found no increased risk for childhood leukemia or pediatric brain tumors, regardless of exposure levels. Occupational exposure to RF, measured by cumulative exposure models, was not linked to a heightened risk for glioma or other tumors.

Study Limitations and Caution in Interpretation

Despite the comprehensive nature of the review, the authors emphasized several limitations. Challenges included missing data, potential biases (such as selection, recall, and publication bias), and possible misclassification or uncontrolled confounding. Notably, the small number of studies related to pediatric brain tumors and fixed-site transmitters means that these findings should be interpreted with caution.

“The evidence rating regarding pediatric brain tumors in relation to environmental RF exposure from fixed-site transmitters should be interpreted with caution, due to the small number of studies,” the researchers concluded.

Overall, the systematic review offers reassuring evidence that RF exposure—whether from mobile phones, cordless phones, environmental sources, or workplace exposure—does not significantly increase the risk of cancer. Although the findings help address concerns about wireless technology and public health, the researchers recommend further investigation into specific areas, such as tumor location and other long-term health effects.

Reference:

1. Environmental International, vol. 169, 2024. Accessed October 11, 2024. https://www.sciencedirect.com/science/article/pii/S0160412024005695.

(Input From Various Sources)

(Rehash/Ankur Deka/MSM)