A simple blood test can identify women at risk of preeclampsia, a leading cause of maternal death, during pregnancy. Researchers have discovered that calculating the ratio of two blood proteins, fibrinogen and albumin, can predict a woman's risk of developing preeclampsia.
A Major Health Concern:
Preeclampsia affects 5-10% of pregnant women, causing sudden high blood pressure and protein in the urine. If left undetected, it can lead to severe complications, including maternal mortality, post-partum bleeding, liver failure, kidney failure, fetal distress, preterm birth, and stillbirth.
A study analyzing 2,629 women's records found that those with a higher fibrinogen-to-albumin ratio (FAR) were more likely to develop preeclampsia. The predicted likelihood of preeclampsia was 24% for women with a FAR of 0.1 and 41% for those with a FAR above 0.3.
Obstetricians and anesthesiologists can take extra precautions if a woman is identified as high-risk for preeclampsia. These measures include frequent blood pressure checks, lab tests, and early epidural placement for pain management.
Preeclampsia is a public health problem worldwide, with:
Seven times higher incidence in developing countries
Late detection contributing to maternal mortality
This breakthrough crucial for improving maternal health outcomes globally
These measures include:
Frequent blood pressure checks
Lab tests
Early epidural placement for pain management
Close monitoring of fetal health
Timely interventions to prevent complications
Currently, uterine artery Doppler ultrasound and other tests are used to assess preeclampsia risk. Incorporating FAR into routine prenatal care could provide an additional tool for early identification.
Preeclampsia is a public health problem worldwide, with a seven times higher incidence in developing countries. The discovery of FAR as a predictive tool for preeclampsia offers hope for improving maternal health outcomes. Early detection and timely interventions can save lives and prevent complications. Late detection contributes to maternal mortality, making this breakthrough crucial for improving maternal health outcomes.
(Input From Various Sources)
(Rehash/Neha Kamble/MSM)
